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Activation of the PI3K/AKT Pathway in Merkel Cell Carcinoma

Merkel cell carcinoma (MCC) is a highly aggressive skin cancer with an increasing incidence. The understanding of the molecular carcinogenesis of MCC is limited. Here, we scrutinized the PI3K/AKT pathway, one of the major pathways activated in human cancer, in MCC. Immunohistochemical analysis of 41...

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Autors principals: Hafner, Christian, Houben, Roland, Baeurle, Anne, Ritter, Cathrin, Schrama, David, Landthaler, Michael, Becker, Juergen C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281946/
https://ncbi.nlm.nih.gov/pubmed/22363598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031255
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