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Bax Deletion Further Orders the Cell Death Pathway in Cerebellar Granule Cells and Suggests a Caspase-independent Pathway to Cell Death

Dissociated cerebellar granule cells maintained in medium containing 25 mM potassium undergo an apoptotic death when switched to medium with 5 mM potassium. Granule cells from mice in which Bax, a proapoptotic Bcl-2 family member, had been deleted, did not undergo apoptosis in 5 mM potassium, yet di...

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Detalhes bibliográficos
Main Authors: Miller, Timothy M., Moulder, Krista L., Knudson, C. Michael, Creedon, Douglas J., Deshmukh, Mohanish, Korsmeyer, Stanley J., Johnson, Eugene M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139809/
https://ncbi.nlm.nih.gov/pubmed/9314540
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