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Cardiac G(sα) overexpression enhances L-type calcium channels through an adenylyl cyclase independent pathway

The α subunit of the stimulatory heterotrimeric G protein (G(sα)) is critical for the β-adrenergic receptor activation of the cAMP messenger system. The role of G(sα) in regulating cardiac Ca(2+) channel activity, however, remains controversial. Cultured neonatal cardiac myocytes from transgenic mic...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Lader, Alan S., Xiao, Yong-Fu, Ishikawa, Yoshihiro, Cui, Yanning, Vatner, Dorothy E., Vatner, Stephen F., Homcy, Charles J., Cantiello, Horacio F.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21397/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9689139/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.16.9669
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