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GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO : II. EFFECT OF REPEATED EXPOSURE TO ALLOANTIGENS ON THE CYTOTOXIC ACTIVITY OF LONG-TERM MIXED LEUKOCYTE CULTURES
Mouse cytotoxic T lymphocytes (CTL) were generated in unidirectional mixed leukocyte cultures (MLC) using normal C57BL/6 spleen cells as responding cells and irradiated DBA/2 spleen cells as stimulating cells. Cytotoxicity was assayed on (51)Cr-labeled P-815 (DBA/2) target cells, and the relative fr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1974
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2139618/ https://ncbi.nlm.nih.gov/pubmed/4278109 |
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