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STUDIES IN PORPHYRIA : I. A DEFECT IN THE REDUCTIVE TRANSFORMATION OF NATURAL STEROID HORMONES IN THE HEREDITARY LIVER DISEASE, ACUTE INTERMITTENT PORPHYRIA
A variety of 5β steroid metabolites derived from hormones natural to man are potent inducers experimentally of δ-aminolevulinate synthetase, the rate-limiting enzyme in porphyrin-heme formation. This mitochondrial enzyme is found at high levels of activity in the livers of patients with the genetic...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
1972
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2139305/ https://ncbi.nlm.nih.gov/pubmed/4263649 |
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