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STUDIES IN PORPHYRIA : I. A DEFECT IN THE REDUCTIVE TRANSFORMATION OF NATURAL STEROID HORMONES IN THE HEREDITARY LIVER DISEASE, ACUTE INTERMITTENT PORPHYRIA

A variety of 5β steroid metabolites derived from hormones natural to man are potent inducers experimentally of δ-aminolevulinate synthetase, the rate-limiting enzyme in porphyrin-heme formation. This mitochondrial enzyme is found at high levels of activity in the livers of patients with the genetic...

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Hlavní autoři: Kappas, Attallah, Bradlow, H. Leon, Gillette, Peter N., Gallagher, T. F.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1972
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139305/
https://ncbi.nlm.nih.gov/pubmed/4263649
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