High-level expression of a proteolytically sensitive diphtheria toxin fragment in Escherichia coli.

ABM508 is a recombinant fusion protein consisting of the N-terminal 485 amino acids of diphtheria toxin joined to alpha-melanocyte-stimulating hormone. When expressed in Escherichia coli under the control of the tox promoter and signal sequence, ABM508 is severely degraded. When overexpressed from a...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Bishai, W R, Rappuoli, R, Murphy, J R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC213919/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3312166/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.169.11.5140-5151.1987
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