IMMUNOPATHOGENESIS OF ACUTE CENTRAL NERVOUS SYSTEM DISEASE PRODUCED BY LYMPHOCYTIC CHORIOMENINGITIS VIRUS : I. CYCLOPHOSPHAMIDE-MEDIATED INDUCTION OF THE VIRUS-CARRIER STATE IN ADULT MICE

A single dose of 150 mg/g of cyclophosphamide (CY), given 3 days after intracerebral (i.c.) inoculation of lymphocytic choriomeningitis (LCM) virus, protected over 90% of adult BALB/c mice against acutely fatal choriomeningitis. Surviving mice became persistently infected carriers, with high virus t...

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Autors principals: Gilden, Donald H., Cole, Gerald A., Monjan, Andrew A., Nathanson, Neal
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1972
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139156/
https://ncbi.nlm.nih.gov/pubmed/4622912
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