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Pathogenesis of Cerebellar Hypoplasia Produced by Lymphocytic Choriomeningitis Virus Infection of Neonatal Rats: Protective Effect of Immunosuppression with Anti-Lymphoid Serum

Intracerebral inoculation of 4-day-old rats with lymphocytic choriomeningitis virus (E-350 strain) produced a nonfatal, acute, severe, and permanent cerebellar necrosis with minimal histological evidence of inflammation. Virus persisted in the brain at high titers for 30 to 40 days and was finally c...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Monjan, Andrew A., Cole, Gerald A., Nathanson, Neal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC422981/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4609903/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.10.3.499-502.1974
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