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Role of the Modular Domains of SR Proteins in Subnuclear Localization and Alternative Splicing Specificity

SR proteins are required for constitutive pre-mRNA splicing and also regulate alternative splice site selection in a concentration-dependent manner. They have a modular structure that consists of one or two RNA-recognition motifs (RRMs) and a COOH-terminal arginine/serine-rich domain (RS domain). We...

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Detalhes bibliográficos
Main Authors: Cáceres, Javier F., Misteli, Tom, Screaton, Gavin R., Spector, David L., Krainer, Adrian R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2138183/
https://ncbi.nlm.nih.gov/pubmed/9230067
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