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Serine Phosphorylation of SR Proteins Is Required for Their Recruitment to Sites of Transcription In Vivo

Expression of most RNA polymerase II transcripts requires the coordinated execution of transcription, splicing, and 3′ processing. We have previously shown that upon transcriptional activation of a gene in vivo, pre-mRNA splicing factors are recruited from nuclear speckles, in which they are concent...

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Bibliographic Details
Main Authors: Misteli, Tom, Cáceres, Javier F., Clement, Jade Q., Krainer, Adrian R., Wilkinson, Miles F., Spector, David L.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132840/
https://ncbi.nlm.nih.gov/pubmed/9786943
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