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Groucho suppresses Pax2 transactivation by inhibition of JNK-mediated phosphorylation

Pax proteins are DNA-binding transcription factors that regulate embryonic development through the activation and repression of downstream target genes. The Pax2 gene is absolutely required for kidney development and for patterning specific regions of the nervous system such as the eye, ear and hind...

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Autors principals: Cai, Yi, Brophy, Patrick D., Levitan, Inna, Stifani, Stefano, Dressler, Gregory R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC213790/
https://ncbi.nlm.nih.gov/pubmed/14532124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg536
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