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Groucho suppresses Pax2 transactivation by inhibition of JNK-mediated phosphorylation

Pax proteins are DNA-binding transcription factors that regulate embryonic development through the activation and repression of downstream target genes. The Pax2 gene is absolutely required for kidney development and for patterning specific regions of the nervous system such as the eye, ear and hind...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Cai, Yi, Brophy, Patrick D., Levitan, Inna, Stifani, Stefano, Dressler, Gregory R.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC213790/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14532124/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg536
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