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Development and characterization of lipidic cochleate containing recombinant factor VIII
Hemophilia A, a life threatening bleeding disorder is caused by deficiency of Factor VIII (FVIII). Replacement therapy using rFVIII is the first line therapy for hemophilia A. However, 15-30% of patients develop neutralizing antibody, mainly against the C2, A3 and A2 domains. It has been reported th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2137893/ https://ncbi.nlm.nih.gov/pubmed/17936245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2007.08.001 |
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