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Bcl-x(L)/Bcl-2 coordinately regulates apoptosis, cell cycle arrest and cell cycle entry

Bcl-x(L) and Bcl-2 inhibit both apoptosis and proliferation. In investigating the relationship between these two functions of Bcl-x(L) and Bcl-2, an analysis of 24 Bcl-x(L) and Bcl-2 mutant alleles, including substitutions at residue Y28 previously reported to selectively abolish the cell cycle acti...

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Detalhes bibliográficos
Main Authors: Janumyan, Yelena M., Sansam, Courtney G., Chattopadhyay, Anuja, Cheng, Ningli, Soucie, Erinn L., Penn, Linda Z., Andrews, David, Knudson, C.Michael, Yang, Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC213787/
https://ncbi.nlm.nih.gov/pubmed/14532118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg533
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