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Human Bcl-2 Reverses Survival Defects in Yeast Lacking Superoxide Dismutase and Delays Death of Wild-Type Yeast

We expressed the human anti-apoptotic protein, Bcl-2, in Saccharomyces cerevisiae to investigate its effects on antioxidant protection and stationary phase survival. Yeast lacking copper-zinc superoxide dismutase (sod1Δ) show a profound defect in entry into and survival during stationary phase even...

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Auteurs principaux: Longo, Valter D., Ellerby, Lisa M., Bredesen, Dale E., Valentine, Joan S., Gralla, Edith B.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1997
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2137818/
https://ncbi.nlm.nih.gov/pubmed/9199172
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