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Sulfonamide resistance in Streptococcus pneumoniae: DNA sequence of the gene encoding dihydropteroate synthase and characterization of the enzyme.

A chromosomal gene of Streptococcus pneumoniae carrying a spontaneous mutation to sulfonamide resistance was identified. Comparison of its DNA sequence with the wild-type sequence showed that the mutation, sul-d, consisted of an insert of 6 base pairs, a repeat of an adjacent 6-base-pair segment. Th...

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Bibliografiska uppgifter
Huvudupphovsmän: Lopez, P, Espinosa, M, Greenberg, B, Lacks, S A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1987
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC213747/
https://ncbi.nlm.nih.gov/pubmed/3114239
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