Sulfonamide resistance in Streptococcus pneumoniae: DNA sequence of the gene encoding dihydropteroate synthase and characterization of the enzyme.

A chromosomal gene of Streptococcus pneumoniae carrying a spontaneous mutation to sulfonamide resistance was identified. Comparison of its DNA sequence with the wild-type sequence showed that the mutation, sul-d, consisted of an insert of 6 base pairs, a repeat of an adjacent 6-base-pair segment. Th...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Lopez, P, Espinosa, M, Greenberg, B, Lacks, S A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC213747/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3114239/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.169.9.4320-4326.1987
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