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GENETICS OF HUMAN CELL LINES : III. INCORPORATION OF 5-BROMO- AND 5-IODODEOXYHRIDINE INTO THE DEOXYRIBONUCLEIC ACID OF HUMAN CELLS AND ITS EFFECT ON RADIATION SENSITIVITY

The human cell line D98S can be cultivated indefinitely in the presence of up to 3 x 10(–5) M 5-bromodeoxyuridine (BUDR), without loss of cell viability. During this time, BUDR is incorporated into both strands of the DNA molecules, replacing up to 45 per cent of the thymidine and thereby rendering...

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Detalhes bibliográficos
Main Authors: Djordjevic, B., Szybalski, Waclaw
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1960
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2137234/
https://ncbi.nlm.nih.gov/pubmed/13723177
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