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GENETICS OF HUMAN CELL LINES : III. INCORPORATION OF 5-BROMO- AND 5-IODODEOXYHRIDINE INTO THE DEOXYRIBONUCLEIC ACID OF HUMAN CELLS AND ITS EFFECT ON RADIATION SENSITIVITY

The human cell line D98S can be cultivated indefinitely in the presence of up to 3 x 10(–5) M 5-bromodeoxyuridine (BUDR), without loss of cell viability. During this time, BUDR is incorporated into both strands of the DNA molecules, replacing up to 45 per cent of the thymidine and thereby rendering...

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Autors principals: Djordjevic, B., Szybalski, Waclaw
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1960
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2137234/
https://ncbi.nlm.nih.gov/pubmed/13723177
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