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AN EARLY EFFECT OF DIPHTHERIA TOXIN ON THE METABOLISM OF MAMMALIAN CELLS GROWING IN CULTURE

At concentrations of 0.1 Lf (0.25 µg.)/ml., or greater, diphtheria toxin produces an immediate decrease (40 ± 5 per cent) in the steady-state level of incorporation of inorganic phosphate into ATP by cultures of normal human kidney cells growing at 37°C. in the presence of glucose. The effect is rea...

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Bibliographic Details
Main Authors: Kato, Iwao, Pappenheimer, A. M.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1960
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2137230/
https://ncbi.nlm.nih.gov/pubmed/13751761
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