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Microinjection of Antibody to Mad2 Protein into Mammalian Cells in Mitosis Induces Premature Anaphase

In yeast, the Mad2 protein is required for the M phase arrest induced by microtubule inhibitors, but the protein is not essential under normal culture conditions. We tested whether the Mad2 protein participates in regulating the timing of anaphase onset in mammalian cells in the absence of microtubu...

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Detalles Bibliográficos
Main Authors: Gorbsky, Gary J., Chen, Rey-Huei, Murray, Andrew W.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2137176/
https://ncbi.nlm.nih.gov/pubmed/9606211
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