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Spatiotemporal Regulation of the Anaphase-Promoting Complex in Mitosis

The appropriate timing of events that lead to chromosome segregation during mitosis and cytokinesis is essential to prevent aneuploidy, and defects in these processes can contribute to tumorigenesis. Key mitotic regulators are controlled through ubiquitylation and proteasome-mediated degradation. Th...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nat Rev Mol Cell Biol
Päätekijät: Sivakumar, Sushama, Gorbsky, Gary J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386896/
https://ncbi.nlm.nih.gov/pubmed/25604195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3934
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