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Spatiotemporal Regulation of the Anaphase-Promoting Complex in Mitosis
The appropriate timing of events that lead to chromosome segregation during mitosis and cytokinesis is essential to prevent aneuploidy, and defects in these processes can contribute to tumorigenesis. Key mitotic regulators are controlled through ubiquitylation and proteasome-mediated degradation. Th...
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| Pubblicato in: | Nat Rev Mol Cell Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4386896/ https://ncbi.nlm.nih.gov/pubmed/25604195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3934 |
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