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Characterization of α1(IV) Collagen Mutations in Caenorhabditis elegans and the Effects of α1 and α2(IV) Mutations on Type IV Collagen Distribution

Type IV collagen is a major component of basement membranes. We have characterized 11 mutations in emb-9, the α1(IV) collagen gene of Caenorhabditis elegans, that result in a spectrum of phenotypes. Five are substitutions of glycines in the Gly-X-Y domain and cause semidominant, temperature-sensitiv...

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Bibliografski detalji
Glavni autori: Gupta, Malini C., Graham, Patricia L., Kramer, James M.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1997
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2136222/
https://ncbi.nlm.nih.gov/pubmed/9166417
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