Mutations in the alpha 2(IV) basement membrane collagen gene of Caenorhabditis elegans produce phenotypes of differing severities.

Type IV collagen forms a network that provides the major structural support of basement membranes. We have determined the nucleotide alterations and phenotypes of 17 mutant alleles of the Caenorhabditis elegans alpha 2(IV) collagen gene let-2. All 17 mutations are within the triple helical (Gly-X-Y)...

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Publicado en:EMBO J
Autores principales: Sibley, M H, Graham, P L, von Mende, N, Kramer, J M
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395224/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8045258/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06629.x
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