Protein Kinase C Activation Upregulates Intercellular Adhesion of α-Catenin–negative Human Colon Cancer Cell Variants via Induction of Desmosomes

The α-catenin molecule links E-cadherin/ β-catenin or E-cadherin/plakoglobin complexes to the actin cytoskeleton. We studied several invasive human colon carcinoma cell lines lacking α-catenin. They showed a solitary and rounded morphotype that correlated with increased invasiveness. These round cel...

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Main Authors: van Hengel, Jolanda, Gohon, Lionel, Bruyneel, Erik, Vermeulen, Stefan, Cornelissen, Maria, Mareel, Marc, van Roy, Frans
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 1997
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2136213/
https://ncbi.nlm.nih.gov/pubmed/9166410
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