An immune cell-selective interleukin 4 agonist

Interleukin 4 (IL-4) is a pleiotropic cytokine. Of the cell types responsive to IL-4, T cells express one IL-4 receptor (IL-4R) type, IL-4Rα/IL-2Rγ (class I IL-4R), whereas endothelial cells express another type, IL-4Rα/IL-13Rα (class II IL-4R). It was hypothesized that IL-4 variants could be genera...

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Huvudupphovsmän: Shanafelt, Armen B., Forte, Carla P., Kasper, James J., Sanchez-Pescador, Lisa, Wetzel, Monte, Gundel, Robert, Greve, Jeffrey M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 1998
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC21359/
https://ncbi.nlm.nih.gov/pubmed/9689101
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