Partition functions of unit-copy plasmids can stabilize the maintenance of plasmid pBR322 at low copy number.
The maintenance of plasmid pBR322 is highly unstable in a polA12 strain of Escherichia coli at 29 degrees C due to severely reduced copy number. Under these conditions, introduction of the par (partition) locus of plasmid P1 or the par (sop) region of F into pBR322 stabilizes it. A region with simil...
Guardat en:
| Publicat a: | J Bacteriol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1986
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC213585/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3536844/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.168.2.1010-1013.1986 |
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