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Partition functions of unit-copy plasmids can stabilize the maintenance of plasmid pBR322 at low copy number.

The maintenance of plasmid pBR322 is highly unstable in a polA12 strain of Escherichia coli at 29 degrees C due to severely reduced copy number. Under these conditions, introduction of the par (partition) locus of plasmid P1 or the par (sop) region of F into pBR322 stabilizes it. A region with simil...

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Detalles Bibliográficos
Publicado en:J Bacteriol
Principais autores: Austin, S, Friedman, S, Ludtke, D
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1986
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC213585/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3536844/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.168.2.1010-1013.1986
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