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The Contribution of Transactivation Subdomains 1 and 2 to p53-Induced Gene Expression Is Heterogeneous But Not Subdomain-Specific

Two adjacent regions within the transactivation domain of p53 are sufficient to support sequence-specific transactivation when fused to a heterologous DNA binding domain. It has been hypothesized that these two subdomains of p53 may contribute to the expression of distinct p53-responsive genes. Here...

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Autors principals: Smith, Jennifer M, Stubbert, Lawton J, Hamill, Jeffrey D, McKay, Bruce C
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press Inc. 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134902/
https://ncbi.nlm.nih.gov/pubmed/18084613
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