Magnetic Resonance Imaging Detection of Tumor Cells by Targeting Low-Density Lipoprotein Receptors with Gd-Loaded Low-Density Lipoprotein Particles

Gd-DO3A-diph and Gd-AAZTAC17 are lipophilic magnetic resonance imaging (MRI) agents that display high affinity for low-density lipoprotein (LDL) particles. However, on binding to LDL, Gd-DO3A-diph shows a decreased hydration that results in a lower enhancement of water proton relaxation rate. Conver...

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Hauptverfasser: Crich, Simonetta Geninatti, Lanzardo, Stefania, Alberti, Diego, Belfiore, Simona, Ciampa, Anna, Giovenzana, Giovanni B, Lovazzano, Clara, Pagliarin, Roberto, Aime, Silvio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2007
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134901/
https://ncbi.nlm.nih.gov/pubmed/18084612
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