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TLR4 signaling induces TLR2 expression in endothelial cells via neutrophil NADPH oxidase

Interactions of polymorphonuclear neutrophils (PMNs) with endothelial cells may contribute to the activation of endothelial cell responses involved in innate immunity. We explored a novel function of PMN NADPH oxidase in the mechanism of Toll-like receptor-2 (TLR2) upregulation induced by LPS-TLR4 s...

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Hlavní autoři: Fan, Jie, Frey, Randall S., Malik, Asrar B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC213490/
https://ncbi.nlm.nih.gov/pubmed/14561708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318696
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