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TLR4 signaling induces TLR2 expression in endothelial cells via neutrophil NADPH oxidase

Interactions of polymorphonuclear neutrophils (PMNs) with endothelial cells may contribute to the activation of endothelial cell responses involved in innate immunity. We explored a novel function of PMN NADPH oxidase in the mechanism of Toll-like receptor-2 (TLR2) upregulation induced by LPS-TLR4 s...

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Detalhes bibliográficos
Main Authors: Fan, Jie, Frey, Randall S., Malik, Asrar B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC213490/
https://ncbi.nlm.nih.gov/pubmed/14561708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318696
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