Dysregulated interferon-gamma responses during lethal cytomegalovirus brain infection of IL-10-deficient mice

Murine cytomegalovirus (MCMV) brain infection induces a transient increase in chemokine production, which precedes the infiltration of CD3(+) lymphocytes. In this study, we hypothesized that an absence of anti-inflammatory cytokines would result in sustained proinflammatory neuroimmune responses. Di...

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Hauptverfasser: Cheeran, Maxim C-J., Hu, Shuxian, Palmquist, Joseph M., Bakken, Thomas, Gekker, Genya, Lokensgard, James R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134841/
https://ncbi.nlm.nih.gov/pubmed/17624463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2007.05.022
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