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CD4(+) Lymphocyte-Mediated Suppression of Cytomegalovirus Expression in Human Astrocytes

Cytomegalovirus-stimulated CD4(+) lymphocytes from seropositive but not seronegative donors suppressed viral gene expression in primary human astrocytes. This suppressive activity was mediated through soluble factors. These findings suggest that CD4(+) lymphocytes play a role in defense of the brain...

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Detalhes bibliográficos
Main Authors: Cheeran, Maxim C.-J., Gekker, Genya, Hu, Shuxian, Yager, Stephanie L., Peterson, Phillip K., Lokensgard, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC95941/
https://ncbi.nlm.nih.gov/pubmed/10882679
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