Overproduction of tyrosyl-tRNA synthetase is toxic to Escherichia coli: a genetic analysis.

The tyrS genes from Escherichia coli and Bacillus stearothermophilus were toxic to E. coli when they were carried by plasmids with very high copy numbers (pEMBL8 and pEMBL9). We quantified this effect by comparing the efficiencies of plating of E. coli derivatives harboring recombinant plasmids in v...

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Pubblicato in:	J Bacteriol
Autori principali:	Bedouelle, H, Guez, V, Vidal-Cros, A, Hermann, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC213377/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2113914/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.7.3940-3945.1990
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