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Overproduction of tyrosyl-tRNA synthetase is toxic to Escherichia coli: a genetic analysis.

The tyrS genes from Escherichia coli and Bacillus stearothermophilus were toxic to E. coli when they were carried by plasmids with very high copy numbers (pEMBL8 and pEMBL9). We quantified this effect by comparing the efficiencies of plating of E. coli derivatives harboring recombinant plasmids in v...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Bedouelle, H, Guez, V, Vidal-Cros, A, Hermann, M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC213377/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2113914/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.7.3940-3945.1990
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