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Critical Role for Cholesterol in Lyn-mediated Tyrosine Phosphorylation of FcεRI and Their Association with Detergent-resistant Membranes
Tyrosine phosphorylation of the high affinity immunoglobulin (Ig)E receptor (FcεRI) by the Src family kinase Lyn is the first known biochemical step that occurs during activation of mast cells and basophils after cross-linking of FcεRI by antigen. The hypothesis that specialized regions in the plasm...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2133197/ https://ncbi.nlm.nih.gov/pubmed/10330413 |
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