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Nuclear Import of the TATA-binding Protein: Mediation by the Karyopherin Kap114p and a Possible Mechanism for Intranuclear Targeting

Binding of the TATA-binding protein (TBP) to the promoter is the first and rate limiting step in the formation of transcriptional complexes. We show here that nuclear import of TBP is mediated by a new karyopherin (Kap) (importin) family member, Kap114p. Kap114p is localized to the cytoplasm and nuc...

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Bibliografische gegevens
Hoofdauteurs: Pemberton, Lucy F., Rosenblum, Jonathan S., Blobel, Günter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2133169/
https://ncbi.nlm.nih.gov/pubmed/10385521
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