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Role of Phosphorylation Sites and the C2 Domain in Regulation of Cytosolic Phospholipase A(2)
Cytosolic phospholipase A(2) (cPLA(2)) mediates agonist-induced arachidonic acid release, the first step in eicosanoid production. cPLA(2) is regulated by phosphorylation and by calcium, which binds to a C2 domain and induces its translocation to membrane. The functional roles of phosphorylation sit...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
1999
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2133140/ https://ncbi.nlm.nih.gov/pubmed/10366595 |
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