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Structural and Functional Regulation of Tight Junctions by RhoA and Rac1 Small GTPases

Tight junctions (TJ) govern ion and solute diffusion through the paracellular space (gate function), and restrict mixing of membrane proteins and lipids between membrane domains (fence function) of polarized epithelial cells. We examined roles of the RhoA and Rac1 GTPases in regulating TJ structure...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jou, Tzuu-Shuh, Schneeberger, Eveline E., James Nelson, W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2133025/
https://ncbi.nlm.nih.gov/pubmed/9660866
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