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Mammalian p55CDC Mediates Association of the Spindle Checkpoint Protein Mad2 with the Cyclosome/Anaphase-promoting Complex, and is Involved in Regulating Anaphase Onset and Late Mitotic Events

We have investigated the function of p55CDC, a mammalian protein related to Cdc20 and Hct1/Cdh1 in Saccharomyces cerevisiae, and Fizzy and Fizzy-related in Drosophila. Immunofluorescence studies and expression of a p55CDC-GFP chimera demonstrate that p55CDC is concentrated at the kinetochores in M p...

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Bibliographische Detailangaben
Hauptverfasser: Kallio, Marko, Weinstein, Jasminder, Daum, John R., Burke, Daniel J., Gorbsky, Gary J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132789/
https://ncbi.nlm.nih.gov/pubmed/9628895
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