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A Single Point Mutation Controls the Cholesterol Dependence of Semliki Forest Virus Entry and Exit

Membrane fusion and budding are key steps in the life cycle of all enveloped viruses. Semliki Forest virus (SFV) is an enveloped alphavirus that requires cellular membrane cholesterol for both membrane fusion and efficient exit of progeny virus from infected cells. We selected an SFV mutant, srf-3,...

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Detalhes bibliográficos
Main Authors: Vashishtha, Malini, Phalen, Thomas, Marquardt, Marianne T., Ryu, Jae S., Ng, Alice C., Kielian, Margaret
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132589/
https://ncbi.nlm.nih.gov/pubmed/9425157
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