A Single Point Mutation Controls the Cholesterol Dependence of Semliki Forest Virus Entry and Exit

Membrane fusion and budding are key steps in the life cycle of all enveloped viruses. Semliki Forest virus (SFV) is an enveloped alphavirus that requires cellular membrane cholesterol for both membrane fusion and efficient exit of progeny virus from infected cells. We selected an SFV mutant, srf-3,...

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Main Authors: Vashishtha, Malini, Phalen, Thomas, Marquardt, Marianne T., Ryu, Jae S., Ng, Alice C., Kielian, Margaret
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1998
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132589/
https://ncbi.nlm.nih.gov/pubmed/9425157
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