A gene required for very short patch repair in Escherichia coli is adjacent to the DNA cytosine methylase gene.
Deamination of 5-methylcytosine in DNA results in T/G mismatches. If unrepaired, these mismatches can lead to C-to-T transition mutations. The very short patch (VSP) repair process in Escherichia coli counteracts the mutagenic process by repairing the mismatches in favor of the G-containing strand....
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| Pubblicato in: | J Bacteriol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
1990
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC213244/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2198248/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.172.8.4214-4221.1990 |
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