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Escherichia coli K-12 clones that overproduce dam methylase are hypermutable.

A strain of Escherichia coli K-12 that overproduces dam methylase 50-fold was found to be hypermutable, and mutations which resulted in loss of excess methylase activity restored mutation frequencies to wild-type levels. These results are consistent with involvement of this deoxyribonucleic acid met...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Herman, G E, Modrich, P
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC217318/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7007328/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.145.1.644-646.1981
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