Autoregulation of the Raf-1 serine/threonine kinase

The Raf-1 serine/threonine kinase is a key protein involved in the transmission of many growth and developmental signals. In this report, we show that autoinhibition mediated by the noncatalytic, N-terminal regulatory region of Raf-1 is an important mechanism regulating Raf-1 function. The inhibitio...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Cutler, Richard E., Stephens, Robert M., Saracino, Misty R., Morrison, Deborah K.
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1998
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21318/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9689060/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.16.9214
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