Autoregulation of the Raf-1 serine/threonine kinase
The Raf-1 serine/threonine kinase is a key protein involved in the transmission of many growth and developmental signals. In this report, we show that autoinhibition mediated by the noncatalytic, N-terminal regulatory region of Raf-1 is an important mechanism regulating Raf-1 function. The inhibitio...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1998
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21318/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9689060/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.16.9214 |
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