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Hepatocyte nuclear factor-1 acts as an accessory factor to enhance the inhibitory action of insulin on mouse glucose-6-phosphatase gene transcription

Glucose-6-phosphatase catalyzes the terminal step in the gluconeogenic and glycogenolytic pathways. Transcription of the gene encoding the glucose-6-phosphatase catalytic subunit (G6Pase) is stimulated by cAMP and glucocorticoids whereas insulin strongly inhibits both this induction and basal G6Pase...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Streeper, Ryan S., Eaton, Erin M., Ebert, Daniel H., Chapman, Stacey C., Svitek, Christina A., O’Brien, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21317/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9689059/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.16.9208
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