Hepatocyte nuclear factor-1 acts as an accessory factor to enhance the inhibitory action of insulin on mouse glucose-6-phosphatase gene transcription

Glucose-6-phosphatase catalyzes the terminal step in the gluconeogenic and glycogenolytic pathways. Transcription of the gene encoding the glucose-6-phosphatase catalytic subunit (G6Pase) is stimulated by cAMP and glucocorticoids whereas insulin strongly inhibits both this induction and basal G6Pase...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Streeper, Ryan S., Eaton, Erin M., Ebert, Daniel H., Chapman, Stacey C., Svitek, Christina A., O’Brien, Richard M.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1998
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21317/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9689059/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.16.9208
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