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Production of infectious virus and degradation of APOBEC3G are separable functional properties of human immunodeficiency virus type 1 Vif

HIV-1 Vif regulates viral infectivity by inhibiting the encapsidation of APOBEC3G (APO3G) through proteasomal degradation of the protein. Here we compared various Vif proteins for their ability to induce APO3G degradation and rescue viral infectivity. We found that Vif expressed from proviral vector...

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Bibliografske podrobnosti
Main Authors: Kao, Sandra, Goila-Gaur, Ritu, Miyagi, Eri, Khan, Mohammad A., Opi, Sandrine, Takeuchi, Hiroaki, Strebel, Klaus
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2129170/
https://ncbi.nlm.nih.gov/pubmed/17825339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.08.005
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