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Inhibition of VEGF Expression and Corneal Neovascularization by siRNA Targeting Cytochrome P450 4B1

Injury to the cornea leads to formation of mediators that initiate and amplify inflammatory responses and neovascularization. Among these are lipid mediators generated by a cytochrome P450 (CYP) enzyme identified as CYP4B1. Increased corneal CYP4B1 expression increases limbal angiogenic activity thr...

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Библиографические подробности
Главные авторы: Seta, Francesca, Patil, Kiran, Bellner, Lars, Mezentsev, Alexandre, Kemp, Rowena, Dunn, Michael W., Schwartzman, Michal Laniado
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128778/
https://ncbi.nlm.nih.gov/pubmed/17991614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2007.05.001
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